Sunday, March 31, 2013

Geno, KC in feeling out stage

CampbellGetty Images

When the Browns signed quarterback Jason Campbell, many assumed he?d potentially become the team?s starter in 2013.? And he?ll definitely get a chance to win the job, since he?s the first signal-caller signed by the new regime in Cleveland, after previously starting in Washington and Oakland.

For now, though, he?s getting paid like a backup, and not a lot when compared to other backups.? A source with knowledge of the contract tells PFT that Campbell?s contract pays out $1.5 million in 2013.

Specifically, he gets a base salary of $1.5 million in 2013, $500,000 of which is fully guaranteed.

That said, if Campbell can win the job, he?ll make more money via incentives.? Specifically, he gets $150,000 for 50 percent playing time in 2013, 65 percent results in $350,000, and 80 percent triggers $600,000.

In 2014, Campbell?s base salary is a bit higher, at $2 million.? He also gets roster bonus of $250,000 due the third day of the league year.

But there are escalators for 2014 based on playing time in the coming season.? Campbell?s 2014 base salary will increase by $500,000 based on 30 percent playing time in 2013.? 40 percent playing time in 2013 increases the 2014 salary by another $500,000.? Ten more percent in 2013?? Another $500,000 in 2014.? And if Campbell takes 65 percent or more of the snaps in 2013, his $2 million salary will double.

Still, his backup pay for 2013 is low, and that?s largely because Campbell?s options were limited.? Especially in light of the egg he laid when he had a chance during 2012 to sub for Jay Cutler in Chicago, during that Monday night debacle against the 49ers.

Campbell could have stayed in Chicago and backed up Cutler, or he could have gone to Cleveland with a chance to win the starting job.? If Campbell pulls it off, he?ll be paid more on the back end.

And if he plays really well in 2013, the Browns likely will tear up the 2014 deal and sign him to something better.

Source: http://profootballtalk.nbcsports.com/2013/03/30/geno-smith-hopes-chiefs-are-legitimately-interested/related/

Butterball mashed potatoes Apple Black Friday how to cook a turkey emma stone Frys tryptophan

Satechi 10-Port USB 3.0 Hub

By Ahmer Kazi Who can argue with having more USB ports? This question rings especially true in an age where folks typically have more USB-enabled devices than available USB ports on our PCs. The Satechi 10-Port USB 3.0 Hub ($69.99 list) aims to address this imbalance by serving up a hub that adds a net gain of nine additional USB 3.0 ports and can charge tablet devices like the Apple iPad. Although it's somewhat pricey and requires an external power supply, it nonetheless succeeds in multiplying your connectivity options more than any of the ports that we've seen thus far. If you have a bunch of peripherals or are simply tired of constantly swapping devices in your system's USB ports, it's worth checking out.

The 10-Port USB 3.0 Hub's plastic chassis measures 1.06 by 1.75 by 8.69 inches (HWD), resulting in a long thin strip that looks a lot like a surge protector. While its glossy black finish is easy on the eyes and complements its array of blue USB 3.0 ports and LED lights, it also attracts a considerable amount of smudges and fingerprints much like the Satechi Slim Surge Protector. Although, the 10-Port USB 3.0 Hub itself is slim enough to slip into your laptop bag or place on your desk without occupying too much space, its power supply adds some bulk.

As its name suggests, there's a total of ten USB 3.0 ports on the 10-Port USB 3.0 Hub. It connects to your system via the included USB 3.0 cable, and the net gain of nine USB 3.0 ports yields far more connectivity options than either the Satechi Ultra Portable 4 Port USB Pocket Hub or the Targus Ultralife USB Hub with Ethernet Port.

Nine of the 10-Port USB 3.0 Hub's USB 3.0 ports are housed on the face of the hub. These nine ports are divided into groups of three, and three corresponding switches on the front panel's left side control the power supply for each group. When switched on, a blue LED accordingly illuminates the corresponding trio of ports. Thanks to the 10-Port USB 3.0 Hub's strip-shape design, there's enough space to prevent neighboring ports from overcrowding one another. The 10-Port USB 3.0 Hub's tenth and final USB port, meanwhile, sits alone on the right panel alongside its own dedicated on/off switch. Unlike the 0.9 amp of power found in the other nine ports, this particular port provides 2.1 amps, and its increased amperage allows it to charge iPads and other similarly-sized tablets.

During testing, the 10-Port USB 3.0 Hub worked just as one would expect, and I experienced no difference in performance when transferring a 1.22GB test folder from a flash drive plugged directly into my computer and when it was plugged into the 10-Port USB 3.0 Hub. The 10-Port USB 3.0 Hub is compatible with Windows (98SE/ME/2000/XP/Vista/7/8) and Mac (OS 9.1 or later), and since it's a plug-and-play device, setting it up requires little beyond plugging it into one of your system's USB ports and a power outlet. Like the Satechi 3.0 4-Port USB Hub, it relies on an external power source. While I typically prefer bus-powered hubs for their unfettered portability, this shortcoming is more forgivable in the case of the 10-Port USB 3.0 Hub since it requires more electric current stability for its considerable amount of ports and tablet-charging capability.

All said, the Satechi 10-Port USB 3.0 Hub is an efficient way to multiply your USB 3.0 connectivity options. Although it costs a bit more than the competitors and requires an external power supply, these shortcomings are understandable considering its net gain of nine USB 3.0 ports and compact size. If you find yourself juggling a bunch of peripherals or have simply grown tired of constantly swapping peripherals out of your USB ports, it's worth checking out.

Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/DdZT60s8qOY/0,2817,2417216,00.asp

Mother Jones cars Bacon Number Kate Middleton photos Chi Magazine Kate Middleton Nude Photos glee

Researchers show stem cell fate depends on 'grip'

Friday, March 29, 2013

The field of regenerative medicine holds great promise, propelled by greater understanding of how stem cells differentiate themselves into many of the body's different cell types. But clinical applications in the field have been slow to materialize, partially owing to difficulties in replicating the conditions these cells naturally experience.

A team of researchers from the University of Pennsylvania has generated new insight on how a stem cell's environment influences what type of cell a stem cell will become. They have shown that whether human mesenchymal stem cells turn into fat or bone cells depends partially on how well they can "grip" the material they are growing in.

The research was conducted by graduate student Sudhir Khetan and associate professor Jason Burdick, along with professor Christopher Chen, all of the School of Engineering and Applied Science's Department of Bioengineering. Others involved in the study include Murat Guvendiren, Wesley Legant and Daniel Cohen.

Their study was published in the journal Nature Materials.

Much research has been done on how stem cells grow on two-dimensional substrates, but comparatively little work has been done in three dimensions. Three-dimensional environments, or matrices, for stems cells have mostly been treated as simple scaffolding, rather than as a signal that influences the cells' development.

Burdick and his colleagues were interested in how these three-dimensional matrices impact mechanotransduction, which is how the cell takes information about its physical environment and translates that to chemical signaling.

"We're trying to understand how material signals can dictate stem cell response," Burdick said. "Rather than considering the material as an inert structure, it's really guiding stem cell fate and differentiation ? what kind of cells they will turn into."

The mesenchymal stem cells the researchers studied are found in bone marrow and can develop into several cell types: osteoblasts, which are found in bone; chondrocytes, which are found in cartilage; and adipocytes, which are found in fat.

The researchers cultured them in water-swollen polymer networks known as hydrogels, which share some similarities with the environments stem cells naturally grow in. These materials are generally soft and flexible ? contact lenses, for example, are a type of hydrogel ? but can vary in density and stiffness depending on the type and quantity of the bonds between the polymers. In this case, the researchers used covalently cross-linked gels, which contain irreversible chemical bonds.

When seeded on top of two-dimensional covalently cross-linked gels, mesenchymal stem cells spread and pulled on the material differently depending on how stiff it was. Critically, the mechanics guide cell fate, or the type of cells they differentiate it into. A softer environment would produce more fat-like cells and a stiffer environment, where the cells can pull on the gel harder, would produce more bone-like cells.

However, when the researchers put mesenchymal stem cells inside three-dimensional hydrogels of varying stiffness, they didn't see these kinds of changes.

"In most covalently cross-linked gels, the cells can't spread into the matrix because they can't degrade the bonds ? they all become fat cells," Burdick said. "That tells us that in 3D covalent gels the cells don't translate the mechanical information the same way they do in a 2D system."

To test this, the researchers changed the chemistry of their hydrogels so that the polymer chains were connected by a peptide that the cells could naturally degrade. They hypothesized that, as the cells spread, they would be able to get a better grip on their surrounding environment and thus be more likely to turn into bone-like cells.

In order to determine how well the cells were pulling on their environment, the researchers used a technique developed by Chen's lab called 3D traction force microscopy. This technique involves seeding the gel with microscopic beads, then tracking their location before and after a cell is removed.

"Because the gel is elastic and will relax back into its original position when you remove the cells," Chen said, "you can quantify how much the cells are pulling on the gel based on how much and which way it springs back after the cell is removed."

The results showed that the stem cells' differentiation into bone-like cells was aided by their ability to better anchor themselves into the growth environment.

"With our original experiment, we observed that the cells essentially didn't pull on the gel. They adhered to it and were viable, but we did not see bead displacement. They couldn't get a grip," Burdick said. "When we put the cells into a gel where they could degrade the bonds, we saw them spread into the matrix and deform it, displacing the beads."

As an additional test, the researchers synthesized another hydrogel. This one had the same covalent bonds that the stem cells could naturally degrade and spread through but also another type of bond that could form when exposed to light. They let the stem cells spread as before, but at the point the cells would begin to differentiate ? about a week after they were first encapsulated ? the researchers further "set" the gel by exposing it to light, forming new bonds the cells couldn't degrade.

"When we introduced these cross-links so they could no longer degrade the matrix, we saw an increase toward fat-like cells, even after letting them spread," Burdick said. "This further supports the idea that continuous degradation is needed for the cells to sense the material properties of their environment and transduce that into differentiation signals."

Burdick and his colleagues see these results as helping develop a better fundamental understanding of how to engineer tissues using stem cells.

"This is a model system for showing how the microenvironment can influence the fate of the cells," Burdick said.

###

University of Pennsylvania: http://www.upenn.edu/pennnews

Thanks to University of Pennsylvania for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 58 time(s).

Source: http://www.labspaces.net/127524/Researchers_show_stem_cell_fate_depends_on__grip__

randy travis Allyson Felix Kourtney Kardashian Baby Girl Ashton Eaton London 2012 basketball London 2012 Slalom Canoe Alex Morgan

CUNY Transfers and New Facilities Drive Access and Expand ...

Transfer students are streaming into the University?s four-year baccalaureate colleges at unprecedented rates ? expanding diversity as a CUNY redefined by a decade of improved academics, record-breaking enrollments and $1.8 billion in campus facility upgrades is increasing access to a high-value education as never before.

The upward transfer trend, evident among all major racial and ethnic groups ? Asians, blacks, Hispanics and whites ? has enhanced racial diversity at the 11 senior colleges, where transfers increased from 15,423 in 2001-2002 to 24,056 in 2011-2012.

The trend not only spotlights an increasingly well-trod path of access to CUNY?s baccalaureate programs, but robust mobility within its more tightly integrated system of colleges. A majority ? 62 percent ? of the transfers came from within the University, and almost all of the within-CUNY transfers, 87 percent, moved from a less-selective college to a more selective one, according to the Office of Institutional Research.
Broken down by race, the 10-year transfer trend is a significant factor in expanding CUNY?s diversity ? already a given with the overwhelming number of freshmen entering from New York City?s diverse public and private high school systems.
From 2001-2002 to 2011-2012, Asian transfer enrollment in the four-year colleges went up from 2,230 to 4,593 or 19.1 percent of the transfer enrollment; black transfer enrollment increased from 4,473 to 5,879, or 24.4 percent; Hispanic transfers climbed from 3,151 to 5,651 or 23.5 percent of baccalaureate transfer enrollment, and white transfer numbers went up from 5,539 to 7,884 or 32.8 percent.

These trends, along with a decade of improving one-year retention rates among black and Hispanic full-time freshmen in the baccalaureate programs, have contributed to steady increases in black and Hispanic baccalaureate enrollment. This diverse profile is likely to remain stable for the foreseeable future, based on the improving retention rates, rising graduation rates at the CUNY-feeding New York City public schools, and the upward transfer trend.

CUNY is one of the most diverse public university systems in the country ? with black, Hispanic and white students each representing more than a quarter of all undergraduates, and Asians 18 percent ? according to fall 2011 figures. In fact, the University has the highest percentage of blacks enrolled in senior colleges, the second-highest percentage of Asians and the third highest percentage of Hispanics when compared with the six other largest and most diverse public systems, including the State University of New York and systems in California, Connecticut, Florida, New Jersey and Texas, according to the National Center for Education Statistics? Integrated Postsecondary Education Data System. Students hail from 208 countries of origin, 58 percent of undergraduates are female, and 28 percent of students are 25 or older.

The University?s community college enrollment has also increased among all racial groups from fall 2001 to fall 2011, according to University figures. The surge been fueled in part by transfer students, whose enrollment rose from 11,293 in 2001-2002 to 14,713 in 2011-2012, a trend reflected among all racial/ethnic groups.

Freshman enrollment also rose substantially at the community colleges ? from 24,217 in 2001-2002 to 34,340 in 2011-2012 ? and took place among all racial groups except for white students, whose freshman numbers have essentially remained stable.

Graduation rates at the University for students of all races have increased dramatically in recent years. The six-year graduation rate for Asian and white students increased 13.8 percentage points between the freshman cohorts of 1995 and 2005, while the graduation rate for black and Hispanic students went up more ? by 14.4 percentage points. Between 2001 and 2011, the number of bachelor?s degrees earned by black students rose 16.3 percent, from 4,055 to 4,714. The number earned by Hispanic students sharply increased by 48.2 percent, from 2,727 to 4,042.

Driven primarily by rising graduation rates in the city?s public high schools, overall undergraduate enrollment at has grown substantially, by 70,000 students, over the past decade. It crested to more than 272,000 ? approximately 105,000 in associate programs and some 114,000 pursuing baccalaureate degrees ? during the 2011-2012 academic year.

The surging demand for classroom seats has been fed by the strengthening of academic standards in the senior colleges, including establishment of The Macaulay Honors College at CUNY and other college-based honors programs ? and the creation of stronger college-
readiness programs in the community colleges including the just-opened, model New Community College at CUNY and the graduation-rate-boosting Accelerated Study in Associate Programs, or ASAP.

The University?s Invest in CUNY campaign has raised $2.3 billion since 2004 to fund initiatives such as student scholarships, and CUNY is now in the
midst of an extensive capital construction program, with $1.8 billion spent so far to expand student capacity at college campuses across the five boroughs.

Antiquated facilities have been upgraded and new buildings housing 21st century classrooms, laboratories, libraries and meeting spaces have been constructed, transforming the CUNY student experience and fueling the city?s economy with steady construction jobs in the process.

Senior, comprehensive and community colleges have all seen significant, value-enhancing facilities improvements. John Jay College of Criminal Justice has a new, $650 million campus on Manhattan?s West Side and has now joined Baruch, Brooklyn, City, Hunter, Queens, Lehman and the
College of Staten Island, in Macaulay Honors College.

Other upgrades at comprehensive and community colleges that have been completed or are underway include Medgar Evers College?s new, $235 million academic building, a $31 million Academic Village at Kingsborough Community College and a new $77 million building at Lehman College showcasing its strength in plant-science education.

At City Tech, a $406 million academic building to address the college?s acute space shortage is under way; at the College of Staten Island, a $200 million interdisciplinary high-performance computational center is in the pipeline, and there are design funds for a $120 million academic village/conference center at York College to house class and conference rooms, a bookstore, student government, clubs and lounges.

This past fall a new library opened at Bronx Community College; Borough of Manhattan Community College?s Fiterman Hall, rebuilt after its destruction on 9/11, opened for classes; and the CUNY Law School moved to a new, modern facility in Long Island City.

CUNY?s integrated system of 24 colleges and schools encompasses 11 senior and comprehensive, and seven community colleges. The new CUNY is expanding academic access and entry points, and upgraded facilities, at all institutional levels ? raising the overall quality of the system while attracting new students to an array of educational opportunities.

Opportunities are also expanding as a result of the University?s increased commitment to adult and continuing education, English-language immersion and GED classes. On-line degree programs coordinated through the School for Professional Studies are also creating new options for returning adults and students in the workforce seeking training and advanced education.

The University has also broadened its educational outreach over the last dozen years through satellite educational centers in city neighborhoods infused with immigrants seeking credit and noncredit courses.

These new points of access include CUNY in the Heights, which recently expanded its program in Washington Heights/Inwood, operated by Hostos Community College and BMCC; CUNY on the Concourse, on Fordham Road in the Bronx, a collaboration with the Local 1199 health care workers? union and run by Lehman, Hostos and BCC; the CUNY Higher Education Center in Flushing, operated by Queensborough Community College; and the new CUNY School of Public Health and Hunter College?s Silberman School of Social Work in East Harlem.
In addition, the University hosts either on campus or nearby more than 20 campus and early college high schools, many offering associate degrees in close collaboration with faculty and teachers from the New York City Department of Education. CUNY?s College Now program partnerships now serve over 20,000 high school students annually, providing free remedial and Advanced Placement courses and seminars at more than 400 public high schools. This is part of CUNY?s long-term commitment to maintain and enhance the student pipeline of college readiness.

About The City University of New York:
The City University of New York is the nation?s leading urban public university. Founded in New York City in 1847, the University is comprised of 24 institutions: 11 senior colleges, seven community colleges, the William E. Macaulay Honors College at CUNY, the CUNY Graduate School and University Center, the CUNY Graduate School of Journalism, the CUNY School of Law, the CUNY School of Professional Studies and the CUNY School of Public Health at Hunter College. The University serves more than 269,000 degree credit students and 218,083 adult, continuing and professional education students.College Now, the University?s academic enrichment program, is offered at CUNY campuses and more than 300 high schools throughout the five boroughs of NewYork City. The University offers online baccalaureate degrees through the School of Professional Studies and an individualized baccalaureate through the CUNY Baccalaureate Degree. Nearly 3 million unique visitors and 10 million page views are served each month via www.cuny.edu, the University?s website.

Source: http://www1.cuny.edu/mu/forum/2013/03/29/cuny-transfers-and-new-facilities-drive-access-and-expand-diversity/

ray lewis alicia keys Harbaugh brothers superbowl commercials randy moss randy moss OJ Brigance

UPS pays $40M to end online pharmacies probe

(AP) ? Shipping company UPS has agreed to pay $40 million to end a federal criminal probe connected to its work for online pharmacies.

The U.S. Department of Justice announced Friday that the Atlanta-based company would also "take steps" to block illicit online drug dealers from using their delivery service.

The DOJ says the fine amount is the money UPS collected from suspect online pharmacies.

UPS won't be charged with any crimes. Its biggest rival, FedEx Corp., has also been a target of the federal investigation.

The investigation of the two companies stems from a global campaign to shutter illicit online pharmacies launched in 2005. Since then, dozens of arrests have been made and thousands of websites closed worldwide as investigators continue to broaden the probe beyond the operators.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-03-29-Online%20Pharmacies-Shippers%20Investigated/id-6987fd7901ad4a01ab3708370479e1d9

derek fisher lyrid meteor shower hippocrates andrew breitbart red wings penguins the band

Saturday, March 30, 2013

Barbara Walters Retirement: Coming in 2014?

Source: http://www.thehollywoodgossip.com/2013/03/barbara-walters-retirement-coming-in-2014/

Nora Ephron mario balotelli mario balotelli espn3 kevin youkilis Tropical Storm Debby legend of korra

Obama touts infrastructure in Florida trip focused on economy

By Jeff Mason

MIAMI (Reuters) - President Barack Obama walked into the mouth of a giant tunnel in Miami on Friday to highlight proposals to boost investment in U.S. infrastructure, a move designed to show a leader still focused on the economy in the midst of broader policy battles in Washington.

Obama's tour of the Port of Miami tunnel project and a subsequent speech were aimed at convincing members of the U.S. Congress to back proposals that would leverage taxpayer dollars into funds to rebuild American roads, bridges and other infrastructure.

"My main message is, let's get this done," he said. "Let's rebuild this country that we love."

Obama, as he has in the past, said he wanted to develop a national infrastructure bank and capitalize it with $10 billion. The idea is to pull in private-sector funding and pick projects based on merit.

He would also create "America Fast Forward Bonds" that would help state and local governments attract money for infrastructure projects. These would be direct subsidy bonds in which the issuer would receive a 28 percent subsidy of the borrowing cost as a way of attracting a wider set of investors.

In addition, Obama would add $4 billion to support two programs that are used to provide grants for infrastructure projects like the Miami tunnel.

It is unclear how far the proposals will go in Congress. Republicans are reluctant to support what they consider government stimulus spending after a much criticized $787 billion stimulus plan that Obama managed to push through Congress in 2009.

Florida's Republican governor, Rick Scott, said his state has been able to improve the Florida economy without Washington's assistance.

"In Florida, we've managed to grow jobs by cutting taxes, paying down debt and balancing the budget - a stark contrast to the ways of Washington," he said.

Obama noted that some people on both sides of the political spectrum, such as labor unions and the Chamber of Commerce, had supported his infrastructure ideas.

"Building bridges and schools, that's not a partisan idea," he said.

Obama was criticized in his first term for focusing too much on his signature policy goal of revamping the U.S. healthcare system, which critics said resulted in him giving less attention to the slow economic recovery.

The White House rejects that charge.

Since his re-election in November and his January inauguration, Obama has steered a policy push focused primarily on passing both immigration reform and tighter gun control measures.

However, his State of the Union address in February included a series of measures to boost the economy, and the Florida trip fleshed out some of those ideas.

Alan Krueger, Obama's chief economist, told reporters traveling with the president on Air Force One that the three main proposals outlined by Obama would cost some $21 billion but that cuts would be made elsewhere to avoid increasing the budget deficit.

Obama's fiscal 2014 budget proposal, which will be released on April 10, would spell out how they are paid for, he said. All of the proposals require congressional approval.

Although Obama will not run for re-election again, Florida is still important for him and his fellow Democrats. The political swing state backed the president in 2012 and will be critical to determining whether a Democrat holds on to the White House or whether a Republican recaptures it in 2016.

The White House believes an increase in infrastructure investment would make the United States more competitive while providing a boost to the construction industry, which is still suffering high levels of unemployment.

(Additional reporting by Steve Holland in Washington; editing by Christopher Wilson)

Source: http://news.yahoo.com/obama-touts-infrastructure-florida-trip-focused-economy-185512785--business.html

hillary rosen j.k. rowling j.k. rowling axl rose google earnings pat burrell hilary rosen

Why Give Corporations a Tax Break? by Laura Tyson - Project ...

BERKELEY ? US President Barack Obama has called for additional revenue as part of a balanced plan to reduce future budget deficits. But he is also proposing a significant cut in the corporate tax rate. To many, this approach seems inconsistent: Shouldn?t the corporate tax rate be raised, not lowered, so that corporations contribute their ?fair share? to deficit reduction? The answer is no.

After its 1986 tax overhaul, the United States had one of the lowest corporate tax rates among OECD countries. Since then, these countries have been slashing their rates in order to attract foreign direct investment and discourage their own companies from shifting operations and profits to low-tax foreign locations. In the most recent and audacious move, the British government has embarked on a three-year plan to reduce its corporate tax rate from 28% to 20% ? one of the lowest in the OECD ? by 2015.

The US now has the highest corporate tax rate of these countries. Even after incorporating various deductions, credits, and other tax-reducing provisions, the effective average and marginal corporate tax rates in the US ? what corporations actually pay ? are higher than the OECD average.

Cutting the rate to a more competitive level would encourage more domestic investment by US corporations, and would also make the US more attractive to foreign investors. Capital has become increasingly mobile, and differences in national corporate tax rates have a growing influence on where multinational companies locate their operations and report their income.

Higher investment in the US by both domestic and foreign companies would boost economic growth, while the resulting increase in capital ??new businesses, factories, equipment, and research ?would improve productivity. That should, in turn, boost real wages over time (although the link between productivity growth and wage growth has weakened during the last two decades).

The pro-growth rationale for reducing the US corporate tax rate is compelling, and explains why Obama has proposed cutting it from 35% to 28% (roughly the weighted average rate of the other developed countries).

But a rate cut would be costly in terms of foregone revenues: each percentage point would reduce corporate-tax revenues by about $100 billion over the next decade. Moreover, recent studies indicate that a significant share of the corporate-tax burden falls on capital, so a reduction in corporate taxes would weaken the progressivity of the tax system at a time when income inequality is at an all-time high.

For these reasons, Obama is championing a ?revenue-neutral? reform that would leave corporate-tax revenues unchanged, with the proposed rate cut financed by limiting deductions, credits, and loopholes, which would broaden the tax base.

These features add complexity to the tax code, raise the cost of tax compliance, and reduce corporate-tax revenues. They also affect business decisions about what to invest in, how to finance investments, which form of business organization to adopt, and where to produce ? reflecting sizeable differences in the effective tax rates behind these choices.

As a result, broadening the corporate tax base will not be easy. Within the corporate sector, the three largest domestic tax preferences are the manufacturing production deduction, the credit for research and development, and accelerated depreciation of capital. Manufacturing companies are the major beneficiaries of these preferences, and Obama has proposed strengthening the first two.

Instead, he suggests reforming the third by tightening allowances for accelerated depreciation (as several other developed countries have done) in order to offset some of the revenue losses. But reducing the overall corporate rate would increase after-tax returns on past investments, while limiting accelerated depreciation would lower after-tax returns on new investments. And even eliminating accelerated depreciation would not broaden the tax base enough to finance a rate cut to 28%.

Likewise, while limiting the deductibility of net interest for corporations, as many other developed countries have done, would broaden the tax base and discourage excessive reliance on debt financing, it would increase the tax burden on major investments in physical capital, which are often debt-financed.

Reducing the tax preferences for non-corporate business entities (such as partnerships) that pass their income through to their owners? individual returns would also broaden the tax base subject to the corporate-income tax. Pass-through companies now account for more than 80% of net business income (by far the highest share in the developed countries). Several of these entities are very large and profitable, and enjoy the same legal benefits as corporations. Economic logic suggests that businesses of similar size and engaged in similar activities should not pay different tax rates based solely on their organizational form.

The fact that a large share of business income is currently taxed as personal income makes it difficult to separate corporate tax reform from personal tax reform, as Obama and members of Congress would prefer to do. Moreover, keeping the two areas of reform separate rules out the approach adopted by several other developed countries, which have offset some of the revenue losses from cutting corporate tax rates by increasing taxes on corporate equity income at the personal shareholder level.

This approach also addresses concerns about the regressive effects of a cut in the corporate rate. It is both more progressive and more effective: with highly mobile capital, it is far easier to collect taxes from individual citizens and resident shareholders than from multinational companies.

According to a recent study, restoring tax rates on dividends and capital gains to their pre-1997 levels of 28% could finance a reduction in the US federal corporate tax rate from 35% to 26%. This change would both reduce the incentive for corporations to shift investments abroad and increase the progressivity of the US tax system.

Similarly, a modest carbon tax or value-added tax, with credits or subsidies to offset the regressive effects on low-income households, could generate enough revenue both to pay for a significant reduction in the corporate tax rate and to make a meaningful contribution to deficit reduction.

There is no inconsistency between a progressive, balanced deficit-reduction plan and lowering the corporate tax rate. Of all taxes, corporate taxes are the most harmful to economic growth ? without which meaningful deficit reduction is far more difficult to achieve.

Reprinting material from this Web site without written consent from Project Syndicate is a violation of international copyright law. To secure permission, please contact us.

Source: http://www.project-syndicate.org/commentary/cutting-us-corporate-taxes-to-stimulate-growth-by-laura-tyson

Pink Floyd 12 12 12 Concert miley cyrus miley cyrus amazing race Cam Cameron Ada Lovelace

Greenwich resident Grainger wins squash title at Chelsea Piers ...

Greenwich resident and Chelsea Piers squash director Natalie Grainger receives her trophy for winning the United States Squash National Championship on her home court.

Greenwich resident and Chelsea Piers squash director Natalie Grainger receives her trophy for winning the United States Squash National Championship on her home court.

For Greenwich resident Natalie Grainger, the timing couldn?t be more perfect for her return to competitive squash.

Grainger, who is the Chelsea Piers Connecticut Racquets Director, got a unique opportunity and made the most of it.

It turns out that Chelsea Piers hosted the United States Squash National Championships and Grainger jumped at the idea of competing once again on her home turf. Not only did Grainger get to play the game she loves, but she won the national championship and reclaimed the No. 1 ranking in the country.

?It was fantastic,? Grainger said. ?To see so many friends and family come to the club to watch and support made it that much more special. There were little kids there watching and being able to produce a good outcome on the day in front of those people that wanted me to win was great.?

During the U.S. Championships Women?s Open Singles event, Grainger was the No. 2 seed and was able to take care of her first round opponent, Niki Clement of Bryn Mawr, Pa. (6,2,5). The semis had Grainger up against Wilton?s Olivia Blatchford, but again it was Grainger with the 4,4,3 victory.

In the championship match, Grainger was up against a familiar foe, top-seed, Amanda Sobhy from Sea Cliff, N.Y. and Grainger won the championship with a score of (8), 3, 3, (5), 7.

?I knew it was going to be a very tough match against Amanda,? Grainger said. ?It meant that in order to win that title, I would have to play a phenomenal opponent, who is on the rise of her own career and she?s someone that I?ve coached and mentored in the past as well. It was a great match and it was clean. Amanda is a champion, so it meant a lot to actually have a tough and accomplished opponent.?

The victory against Sobhy gave Grainger the sixth national championship of her career. However, this title was more rewarding.

During her previous five championship runs, Grainger was an active member on the squash tour and was also ranked one of the top players in the world.

Now things are different. Grainger has been retired from the tour for a few years now and is currently teaching and directing squash full-time at The Squash Club at Chelsea Piers Connecticut, a 12 International court state-of-the-art facility in Stamford.

?I could have showed up with the expectations of really having to play well, but I felt like there wasn?t as much pressure because of being retired,? Grainger said. ?It meant a lot to me to win the event.?

In order to get ready for the championship, Grainger had to change things up a bit. With the success of The Squash Club at Chelsea Piers Connecticut, Grainger has been coaching quite a bit, but didn?t really have the time to play some competitive squash.

Leading up to the national championships, Grainger did her best to prepare. In the weeks before the championship, Grainger got in a couple of matches a week with some of her fellow pros that work at Chelsea Piers and from other pros from around the area.

While lightening her coaching in the days before the tournament, Grainger also entered a tournament in New York and played in the men?s division so she could get a little bit of match practice under her belt.

?We just finished with the height of the season and I just finished coaching in the junior championships, so my focus had to be on them,? Grainger said. ?I was able to get a couple of matches a week with some pros and I entered a tournament in New York and played in the men?s division there, so I could get a little bit of match practice. That was really helpful and that gave me a wake-up call to remind me not to do too much coaching in the lead-up to competing because it makes your legs so heavy. I lightened my coaching mode a day or two leading up to the event.?

While winning the championship in front of all the local supporters was an amazing feeling for Grainger, seeing the Squash Club at Chelsea Piers roar to life was equally exciting.

?The club was able to hold a great championship,? Grainger said. ?Everybody that I talked to had such a phenomenal time at the tournament. The masters players really enjoyed the club and seeing people enjoy the facility and having it spring to life with such a major championship was really exciting.?

Although competing at a high level, as well as winning championships, never gets old, don?t expect to see Grainger giving up coaching the sport she loves any time soon.

?The interesting thing about Chelsea Piers is that we have a lot of kids in our program that have never been exposed to the sport of squash,? Grainger said. ?It?s great to have this facility Chelsea Piers and the ability to take squash outside of some of the private clubs and have kind of an all-access facility. To build a program where kids can enjoy the sport is phenomenal because it?s such a fun sport for young kids to try.?

Source: http://www.greenwich-post.com/12050/greenwich-resident-grainger-wins-national-title-on-home-turf-at-chelsea-piers/

dwight howard Olympics closing ceremony PGA Championship 2012 John Witherspoon george michael usain bolt Closing Ceremony London 2012

Cuomo, Bolduan hosts of CNN morning show

NEW YORK (AP) ? CNN is rebooting its mornings with a new program hosted by Chris Cuomo and Kate Bolduan that will debut later this spring, hoping its behind-the-scenes firepower can create something distinctive for a crowded marketplace.

The show, which will originate in New York and doesn't have a name yet, will also feature Los Angeles local TV anchor Michaela Pereira as the news anchor.

The senior executive producer, Jim Murphy, promised viewers a "different kind of conversation and a fresher and more energetic program than they're used to."

Cuomo jumped from ABC News to CNN largely for the morning opportunity. He was the news anchor at "Good Morning America" from 2006 to 2009 and went to "20/20" after George Stephanopoulos got the main hosting job in the morning.

Bolduan has covered Congress for CNN and been co-host with Wolf Blitzer of "The Situation Room" in the late afternoon.

Both Murphy and his boss, CNN chief executive Jeff Zucker, have extensive morning show experience. Zucker's success as executive producer of the "Today" show in the 1990s helped him move up the executive ranks at NBC. Murphy was the top executive at ABC's "Good Morning America" from 2006 to 2011.

CNN has struggled in the mornings, averaging 252,000 viewers so far this year, the Nielsen company said.

The broadcast networks ABC, NBC and CBS all have morning shows with larger audiences than anything on cable. In cable, CNN's competitors have distinctive programs and personalities: "Fox & Friends," which averages 1.1 million viewers, and MSNBC's "Morning Joe," which has 420,000 viewers. CNN runs close with its sister network, HLN, which airs Robin Meade's morning show (223,000 viewers). Within a youthful news demographic, CNN runs fourth.

Murphy kept much of his plans under wrap for competitive reasons. He said the show will feel familiar to morning news viewers.

"The key to success in this day-part is having great personalities who know how to talk to each other, to their guests and to the public in a way where you just want to be there, with someone you want to have coffee with," he said.

CNN tested and interviewed at least 10 internal and external candidates before settling on Bolduan, who Zucker said left executives "floored with excitement" when they saw her pairing with Cuomo. CNN prime-time anchor Erin Burnett was widely considered to have the inside shot at the job, but she will remain in the evenings.

Murphy said he's still debating whether to have a regular weather forecaster as part of the team. His top deputy will be Matt Frucci.

Source: http://news.yahoo.com/cuomo-bolduan-hosts-cnn-morning-show-141730915.html

islands 2013 nissan altima masters par 3 contest google augmented reality glasses wonderlic test texas tornado fantasy baseball

Fewer children mean longer life?

Thursday, March 28, 2013

New research into ageing processes, based on modern genetic techniques, confirms theoretical expectations about the correlation between reproduction and lifespan. Studies of birds reveal that those that have offspring later in life and have fewer broods live longer. And the decisive factor is telomeres, shows research from The University of Gothenburg, Sweden.

Telomeres are the protective caps at the end of chromosomes. The length of telomeres influences how long an individual lives.

Telomeres start off at a certain length, become shorter each time a cell divides, decline as the years pass by until the telomeres can no longer protect the chromosomes, and the cell dies. But the length of telomeres varies significantly among individuals of the same age. This is partly due to the length of the telomeres that has been inherited from the parents, and partly due to the amount of stress an individual is exposed to.

"This is important, not least for our own species, as we are all having to deal with increased stress," says Angela Pauliny, Researcher from the Department of Biological and Environmental Sciences at the University of Gothenburg.

Researchers have studied barnacle geese, which are long-lived birds, the oldest in the study being 22 years old. The results show that geese, compared to short-lived bird species, have a better ability to preserve the length of their telomeres. The explanation is probably that species with a longer lifespan invest more in maintaining bodily functions than, for example, reproduction.

"There is a clear correlation between reproduction and ageing in the animal world. Take elephants, which have a long lifespan but few offspring, while mice, for example, live for a short time but produce a lot of offspring each time they try," says Angela Pauliny.

The geese studied by researchers varied in age, from very young birds to extremely old ones. Each bird was measured twice, two years apart. One striking result was that the change in telomere length varied according to gender.

"The study revealed that telomeres were best-preserved in males. Among barnacle geese, the telomeres thus shorten more quickly in females, which in birds is the sex with two different gender chromosomes. Interestingly, it is the exactl opposite in humans," says Angela Pauliny.

###

The journal BMC Evolutionary Biology has classified the research article "Telomere dynamics in a long-lived bird, the barnacle goose" as "Highly Accessed".

Link to the article: http://www.biomedcentral.com/1471-2148/12/257

University of Gothenburg: http://www.gu.se/english

Thanks to University of Gothenburg for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 42 time(s).

Source: http://www.labspaces.net/127500/Fewer_children_mean_longer_life_

apple ipad kony kony 2012 jim irsay the new ipad apple announcement indianapolis colts

Rexall's Dubious Homeopathic Offerings | The Business Ethics Blog

The drugstore chain, Rexall, has been shaking things up a bit lately. Chain Drug Review recently posted a lengthy piece on how Rexall ?aims to reinvent the drug store?. And a recent piece in the Ottawa Citizen says that the chain?s new products aim to make life better.

But not all of the attention lavished on Rexall has been so positive. Dr Terry Polevoy, an MD who runs the website Canadian Quackery Watch, recently showed me a highly problematic ad from a Rexall flyer inserted two weeks ago into his local newspaper, the Waterloo Record:

Trusted homeopathic remedies offer an alternative way to naturally treat symptoms. Speak to your local Rexall Pharmacist for more information or visit rexall.ca.

The problem, of course, is that homeopathy doesn?t work. Or, to be more precise, there?s no reliable evidence that it works, nor any plausible reason to think that it even could work. In commercial contexts, that?s pretty bad. And it?s worse still when the company selling the stuff is a company people rely on for competent health advice, and when that company leverages the credibility of a licensed health profession to promote bogus wares.

Rexall isn?t the only drugstore chain selling homeopathy and other ?alternative? healthcare products. A pharmacist friend who keeps his eyes open for such things tells me he?s seeing more and more of it. And last year, a class action lawsuit was filed against Shoppers Drug Mart and a company called Boiron, maker of a homeopathic preparation called ?Oscillococcinum.? The suit alleges that Boiron breached several consumer protection statues in marketing Oscillicoccinum without evidence that it works.

But even if the suit against Shoppers fails, it?s worth remembering that what?s legal isn?t always ethical. It?s wrong to mislead consumers, even where doing so is legal. And the Rexall flyer is clearly misleading. Homeopathic remedies are incapable of treating symptoms ? at least, unless the companies that make them have learned to violate the laws of physics and basic biochemistry. A homeopathic ointment may soothe skin because of the soothing properties of the non-medicinal cream on which it is based ? if you take standard hand cream and add pixie dust it will now be ?pixie dust cream,? but the fact that it makes your skin feel better won?t have anything to do with the power of pixies.

And then there?s the placebo effect, rooted in the well-documented fact that the power of suggestion can in some cases have real physical effects: if you believe a pill will cure your headache, then it just might. But such effects are quite hit-and-miss, and hard to predict, and in any case are predicated on a lie. Lying isn?t always illegal, or even always wrong, but when you lie in commercial contexts, both the law and society more generally takes a pretty dim view of it.

Now to be fair, I know that there are other products on drugstore shelves that raise questions about efficacy. Some studies have suggested that prescription antidepressants, for example, are no more effective than placebos. But the key is that there?s a rigorous (if imperfect) procedure for debating the effectiveness of prescription drugs. Yes, the makers of prescription drugs sometimes exaggerate the effectiveness of their products, playing fast-and-loose with the evidence. But the purveyors of ?alternative? therapies like homeopathy do that literally all the time.

When I asked him what he thought about this kind of marketing, Dr Polevoy said the following:

Rexall, like Shoppers Drug Mart, has one thing in mind when it comes to the marketing of homeopathic products. In my opinion, the bottom line ? profits ? is much more important to them than their customers, and whether or not these products work. Their customers are the ones who will ultimately pay the price, and the pharmacists have no power to warn their customers that homeopathy is bogus, and that they are wasting their money.

The commercial world is full of scams, and all too often people with something to sell have unwarranted faith in their products. Greed and ignorance are nothing new, but that that doesn?t mean they are excusable. Companies that claim not just to provide a product, but to educate and take care of consumers, ought to do better. They should do their best to sell only those products that they, and their customers, are justified in believing in.
Rexall_homeopathy_March14_2013

Like this:

Like Loading...

Source: http://businessethicsblog.com/2013/03/28/rexalls-dubious-homeopathic-offerings/

birth control recall nick carter leslie carter aaron carter sister pfizer signing day 2012 football gasland

Fewer children mean longer life?

Thursday, March 28, 2013

New research into ageing processes, based on modern genetic techniques, confirms theoretical expectations about the correlation between reproduction and lifespan. Studies of birds reveal that those that have offspring later in life and have fewer broods live longer. And the decisive factor is telomeres, shows research from The University of Gothenburg, Sweden.

Telomeres are the protective caps at the end of chromosomes. The length of telomeres influences how long an individual lives.

Telomeres start off at a certain length, become shorter each time a cell divides, decline as the years pass by until the telomeres can no longer protect the chromosomes, and the cell dies. But the length of telomeres varies significantly among individuals of the same age. This is partly due to the length of the telomeres that has been inherited from the parents, and partly due to the amount of stress an individual is exposed to.

"This is important, not least for our own species, as we are all having to deal with increased stress," says Angela Pauliny, Researcher from the Department of Biological and Environmental Sciences at the University of Gothenburg.

Researchers have studied barnacle geese, which are long-lived birds, the oldest in the study being 22 years old. The results show that geese, compared to short-lived bird species, have a better ability to preserve the length of their telomeres. The explanation is probably that species with a longer lifespan invest more in maintaining bodily functions than, for example, reproduction.

"There is a clear correlation between reproduction and ageing in the animal world. Take elephants, which have a long lifespan but few offspring, while mice, for example, live for a short time but produce a lot of offspring each time they try," says Angela Pauliny.

The geese studied by researchers varied in age, from very young birds to extremely old ones. Each bird was measured twice, two years apart. One striking result was that the change in telomere length varied according to gender.

"The study revealed that telomeres were best-preserved in males. Among barnacle geese, the telomeres thus shorten more quickly in females, which in birds is the sex with two different gender chromosomes. Interestingly, it is the exactl opposite in humans," says Angela Pauliny.

###

The journal BMC Evolutionary Biology has classified the research article "Telomere dynamics in a long-lived bird, the barnacle goose" as "Highly Accessed".

Link to the article: http://www.biomedcentral.com/1471-2148/12/257

University of Gothenburg: http://www.gu.se/english

Thanks to University of Gothenburg for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 51 time(s).

Source: http://www.labspaces.net/127500/Fewer_children_mean_longer_life_

ncaa tournament schedule March Madness Live Google Keep ncaa scores Splash Ncaa Basketball Tournament NCAA Bracket 2013

Ars Poetica: Where Art Meets Poetry | Kitsap Week - Port Orchard ...

BREMERTON ? Local artists are honoring National Poetry Month by selecting works by local poets and visually interpreting them.

Interpretations are in two-dimensional and three-dimensional works in a wide range of mediums. View the poems and the art at the First Friday Artwalk, April 5, 5-8 p.m. at these Bremerton venues:
? IZM, 247 4th St.
? Elaine Turso Photography, 249 4th St.
? Valentinetti Puppet Museum, 257 4th St.
? Bremerton Chamber of Commerce, 286 4th St.
? Mistarian Roses, 519 4th St.
? Claywerks Too, 345 6th St., Suite 600.
? Toro Lounge & Tapas, 315 Pacific Ave.?
? Hudson?s Photography, 321 Pacific Ave.
? Collective Visions Gallery, 331 Pacific Ave.
? Amy Burnett Gallery, 408 Pacific Ave.
? Juan Rodriguez, 408 Pacific Ave.
? Two Sisters Fine Jewelry, 520 Pacific Ave.
? Edward Jones Financial, 555 Pacific Ave., No. 101.

The ?Ars Poetica 2013? book features 27 regional poems and 16 CVG artists. To order, email photoartbybev@aol.com. Pre-order price: $10.50.

?

Source: http://www.portorchardindependent.com/entertainment/200510011.html

elizabeth smart south dakota state long beach state beasley trailblazers michael beasley jermaine jones

Friday, March 29, 2013

News in Brief: Termites, not fairies, cause plant circles in African deserts

Underground insect engineers create water traps, allowing rings of green grasses in the sand

Underground insect engineers create water traps, allowing rings of green grasses in the sand

By Susan Milius

Web edition: March 28, 2013

Enlarge

Natural rings of perennial grasses manage to survive in parched terrain of NamibRand, Namibia, thanks to a termite that creates areas of moisture within the sand.

Credit: N. J?rgens

The Namib Desert?s version of crop circles turns out to be the handiwork of sand-dwelling termites.

These ?fairy rings? of perennial grass species dot arid, sandy sweeps from Angola to South Africa and have inspired ecological and mythological speculation about their origins. After 40 trips to study the water distribution and life around the fairy rings, Norbert J?rgens of the University of Hamburg in Germany concludes that the sand termite (Psammotermes allocerus) is the hidden force behind them.

Among the hundreds of species that thrive in these rings, the sand termite is the only one found throughout the range, he reports in the March 29 Science.

Termites unintentionally engineer these marvels by eating the roots of grasses, creating a bald patch that becomes the ring?s center. The subsurface depths of that patch stay moister than neighboring areas, where plants draw the water out of the soil. The circles? bull?s eye favors not only the moisture-loving termites, but also a belt around its edge of perennial grasses and many other species that couldn?t survive baked sand.

As ecosystem engineers, J?rgens says, the sand termite rivals the beaver.

Source: http://www.sciencenews.org/view/generic/id/349261/title/News_in_Brief_Termites_not_fairies_cause_plant_circles_in_African_deserts

sinkhole justin bieber Real Madrid Vs Manchester United Real Madrid Duck Dynasty sequestration Van Cliburn

Canon Pixma PRO-100


The Canon Pixma PRO-100 may be the new junior model in Canon's professional photo inkjet line, but as such it can still output gallery-quality prints at sizes up to 13 by 19 inches. It's a good choice for an amateur photographer who's looking to take the hobby more seriously.

At 8.6 by 27.2 by 15.2 inches (HWD) when closed, it's slightly larger than its Epson counterpart, the Editors' Choice Epson Stylus Photo R2000, and about the same weight. Like the R2000, it lacks an LCD; instructions and data like ink tank levels are displayed on the screen of the computer you're printing from. It offers WiFi and Ethernet as well as USB connectivity.

The PRO-100 uses eight ink tanks for its dye-based inks: black; gray; light gray; yellow; magenta; photo magenta; cyan; and photo cyan. The high-end model in the series, the Canon Pixma PRO-1, sports 12 ink tanks. Although the PRO-100's sticker price is much less than that of the PRO-1, its ink costs?at least in price per milliliter of ink, as there's no good way to measure the cost per printed page for this sort of printer?are considerably higher. Each of its tanks holds 13 ml of ink, at a cost of $1.31 per ml, compared with an even dollar per ml for the PRO-1, which has much higher capacity (36 ml) tanks. The PRO-100's ink costs per ml are also slightly higher than the $1.25 per ml of the Editors' Choice Epson Stylus Photo R2000.

The PIXMA PRO-100 has two paper trays: A rear tray for a variety of fine art and glossy photo papers, and a manual slot for thicker media. It also permits printing onto printable CDs, DVDs, and Blu-ray discs.

Canon Pixma PRO-100

Speed
Speed takes a back seat to quality with near-dedicated photo printers, but faster is still preferable, all else being equal. I timed the Canon Pixma PRO-100 (using QualityLogic's hardware and software) at an average of 1 minute 17 seconds to output a 4-by-6 print and 2:01 to output an 8-by-10. This is slightly slower than the 51 seconds per 4-by-6 and 1:42 per 8-by-10 for the Epson R2000, but much faster than the Canon Pixma PRO-1's 2:14 and 3:53 times.

Output Quality
No one buys a photo printer like the PRO-100 to print text, but it's good to know it can do so if you need it to, as it has above-average quality for an inkjet. It did especially well on several of the more common business fonts. Graphics quality was slightly above par for an inkjet, though colors were off on a couple of illustrations.

It's with photos, though, that the PRO-100 really shines. In our standard photo tests, it did very well in capturing detail in both light and dark areas, and in faces. There was the barest hint of a tint in a monochrome image, but only a perfectionist is likely to notice. I also did some ad-hoc testing, including with larger-format (13 by 19 inches) prints. It didn't do quite as well as the PRO-1 in printing images with very dark backgrounds, which isn't surprising as five of that printer's 12 ink tanks are various shades of black or gray. In a couple of prints, the colors were slightly off. Still, the overall photo quality is good enough to produce prints for exhibition or sale.

The Canon Pixma PRO-1 costs twice as much as the PRO-100 and is bigger, heavier, and slower, but has considerably lower ink costs. The PRO-1 did a superior job of printing photos with black or very dark backgrounds, and did slightly better in printing other photos as well.

The Epson Stylus Photo R3000 ($849.99 direct), which prints top-tier photos and graphics, adds a color LCD and the ability to print from paper rolls.

The Epson R2000 is a touch smaller than the PRO-100 and has a slight edge in speed, as well as slightly lower ink costs (per volume at least). That said, they both produce gallery-worthy prints, and choosing between them may come down to whether you prefer the look of Epson or Canon prints, which have slightly different qualities. They both offer WiFi, Ethernet, and USB connectivity.

Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/rnNTkQCdoLc/0,2817,2417036,00.asp

lindsey vonn nit first day of spring Club Penguin Espn Bracket First Day Of Spring 2013 Suki Waterhouse

Confirmed: Nexus 4 shipping with updated design

Nexus 4 redesign

Small nubs now lift the back of the phone up off a table; camera lens gets a slight redesign

Android Central has confirmed that the Nexus 4 has undergone a little bit of a design tweak. As first reported by German site MobiFlip. there are now a couple of small nubs on the rear of the phone, where the glass meets the foot, positioned just above the two screw holes. 

We've confirmed the change on a pair of Nexus 4s we ordered on Monday this week and received on Wednesday. In the image above, our original Nexus 4, now some four months old, is on top, with a new retail unit (still in its protective plastic) at the bottom. Note the little nub between the screw holes of the two phones.

This small design change has a couple of effects. It lifts phone up ever so slightly, allowing sound to escape the flush speaker. We can confirm that sounds are a little fuller and louder. Not a great deal, but we can tell. The change also should help keep the glass back from getting the little hairline scratches it's been prone to pick up.

And perhaps more important, it should keep the ultra-slick phone from sliding off any similarly slick surfaces.

read more



Source: http://feedproxy.google.com/~r/androidcentral/~3/nbePPktohf4/story01.htm

bowling green marysville tornados dr. seuss the temptations rush limbaugh sandra fluke green book

Taylor Swift to guest star on Fox's 'New Girl'

NEW YORK (AP) ? A new girl is coming to Fox's "New Girl" and her name is Taylor Swift.

A representative for the Grammy-winning singer said Thursday that Swift will appear on the May 14 season finale of the hit show. No other details were provided.

"New Girl" stars actress-singer Zooey Deschanel as the awkward, but bubbly Jessica Day, who lives with three male roommates.

Swift appeared in the 2010 romantic comedy "Valentine's Day" and guest starred on "CSI" in 2009. The 23-year-old launched her "Red" world tour this month.

___

Online:

http://taylorswift.com/

http://www.fox.com/new-girl/

Source: http://news.yahoo.com/taylor-swift-guest-star-foxs-girl-190147183.html

jennie garth space needle nashville predators king arthur king arthur there will be blood there will be blood

Google patent application would tie camera settings to local weather

Google patent application would tie camera settings to weather

GPS is burgeoning into a tool for more than just finding our way, such as choosing gears on a weekend drive. If one of Google's newly published patent applications becomes reality, positioning might also fix our off-color photos. Its proposed technique would use GPS to automatically tune a camera based on both the local climate and whether or not you're outdoors: the white balance and saturation could be different for a sunny day in the park than a rainy day stuck inside, for example. While automatic settings are already commonplace, the method could lead to more accurate output that reduces the urge to flick on a manual mode. There's no guarantee that we'll ever see the patent in a shipping product, but don't be surprised if future Android smartphones produce uncannily good photography with little effort.

Filed under: , , ,

Comments

Source: USPTO

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/r8vhY7GOK4M/

world trade center kirk cousins ovechkin one world trade center bks new dark knight rises trailer khloe and lamar

Surgical menopause may prime brain for stroke, Alzheimer's

Surgical menopause may prime brain for stroke, Alzheimer's [ Back to EurekAlert! ] Public release date: 28-Mar-2013
[ | E-mail | Share Share ]

Contact: Toni Baker
tbaker@gru.edu
706-721-4421
Medical College of Georgia at Georgia Regents University

Women who abruptly and prematurely lose estrogen from surgical menopause have a two-fold increase in cognitive decline and dementia.

"This is what the clinical studies indicate and our animal studies looking at the underlying mechanisms back this up," said Brann, corresponding author of the study in the journal Brain. "We wanted to find out why that is occurring. We suspect it's due to the premature loss of estrogen."

In an effort to mimic what occurs in women, Brann and his colleagues looked at rats 10 weeks after removal of their estrogen-producing ovaries that were either immediately started on low-dose estrogen therapy, started therapy 10 weeks later or never given estrogen.

When the researchers caused a stroke-like event in the brain's hippocampus, a center of learning and memory, they found the rodents treated late or not at all experienced more brain damage, specifically to a region of the hippocampus called CA3 that is normally stroke-resistant.

To make matters worse, untreated or late-treated rats also began an abnormal, robust production of Alzheimer's disease-related proteins in the CA3 region, even becoming hypersensitive to one of the most toxic of the beta amyloid proteins that are a hallmark of Alzheimer's.

Both problems appear associated with the increased production of free radicals in the brain. In fact, when the researchers blocked the excessive production, heightened stroke sensitivity and brain cell death in the CA3 region were reduced.

Interestingly the brain's increased sensitivity to stressors such as inadequate oxygen was gender specific, Brann said. Removing testes in male rats, didn't affect stroke size or damage.

Although exactly how it works is unknown, estrogen appears to help protect younger females from problems such as stroke and heart attack. Their risks of the maladies increase after menopause to about the same as males. Follow up studies are needed to see if estrogen therapy also reduces sensitivity to the beta amyloid protein in the CA3 region, as they expect, Brann noted.

Brann earlier showed that prolonged estrogen deprivation in aging rats dramatically reduces the number of brain receptors for the hormone as well as its ability to prevent strokes. Damage was forestalled if estrogen replacement was started shortly after hormone levels drop, according to the 2011 study in the journal Proceedings of the National Academy of Sciences.

The surprising results of the much-publicized Women's Health Initiative a 12-year study of 161,808 women ages 50-79 found hormone therapy generally increased rather than decreased stroke risk as well as other health problems. Critics said one problem with the study was that many of the women, like Brann's aged rats, had gone years without hormone replacement, bolstering the case that timing is everything.

###

The research was supported by the National Institute of Neurological Disorders and Stroke, an American Heart Association Scientist Development grant and a National Natural Science Foundation grant.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Surgical menopause may prime brain for stroke, Alzheimer's [ Back to EurekAlert! ] Public release date: 28-Mar-2013
[ | E-mail | Share Share ]

Contact: Toni Baker
tbaker@gru.edu
706-721-4421
Medical College of Georgia at Georgia Regents University

Women who abruptly and prematurely lose estrogen from surgical menopause have a two-fold increase in cognitive decline and dementia.

"This is what the clinical studies indicate and our animal studies looking at the underlying mechanisms back this up," said Brann, corresponding author of the study in the journal Brain. "We wanted to find out why that is occurring. We suspect it's due to the premature loss of estrogen."

In an effort to mimic what occurs in women, Brann and his colleagues looked at rats 10 weeks after removal of their estrogen-producing ovaries that were either immediately started on low-dose estrogen therapy, started therapy 10 weeks later or never given estrogen.

When the researchers caused a stroke-like event in the brain's hippocampus, a center of learning and memory, they found the rodents treated late or not at all experienced more brain damage, specifically to a region of the hippocampus called CA3 that is normally stroke-resistant.

To make matters worse, untreated or late-treated rats also began an abnormal, robust production of Alzheimer's disease-related proteins in the CA3 region, even becoming hypersensitive to one of the most toxic of the beta amyloid proteins that are a hallmark of Alzheimer's.

Both problems appear associated with the increased production of free radicals in the brain. In fact, when the researchers blocked the excessive production, heightened stroke sensitivity and brain cell death in the CA3 region were reduced.

Interestingly the brain's increased sensitivity to stressors such as inadequate oxygen was gender specific, Brann said. Removing testes in male rats, didn't affect stroke size or damage.

Although exactly how it works is unknown, estrogen appears to help protect younger females from problems such as stroke and heart attack. Their risks of the maladies increase after menopause to about the same as males. Follow up studies are needed to see if estrogen therapy also reduces sensitivity to the beta amyloid protein in the CA3 region, as they expect, Brann noted.

Brann earlier showed that prolonged estrogen deprivation in aging rats dramatically reduces the number of brain receptors for the hormone as well as its ability to prevent strokes. Damage was forestalled if estrogen replacement was started shortly after hormone levels drop, according to the 2011 study in the journal Proceedings of the National Academy of Sciences.

The surprising results of the much-publicized Women's Health Initiative a 12-year study of 161,808 women ages 50-79 found hormone therapy generally increased rather than decreased stroke risk as well as other health problems. Critics said one problem with the study was that many of the women, like Brann's aged rats, had gone years without hormone replacement, bolstering the case that timing is everything.

###

The research was supported by the National Institute of Neurological Disorders and Stroke, an American Heart Association Scientist Development grant and a National Natural Science Foundation grant.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-03/mcog-smm032813.php

snl lindsay lohan valley fever project x the lorax lorax fisker karma super tuesday states